BDBM50252631 CHEMBL494278::N-(3-((6-chloropyridin-3-yl)methyl)thiazol-2(3H)-ylidene)pyrazine-2-carboxamide

SMILES: Clc1ccc(Cn2ccs\c2=N/C(=O)c2cnccn2)cn1

InChI Key: InChIKey=JZVDFKIEMGFAIS-RGEXLXHISA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50252631   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-4 (Gallus gallus)	BDBM50252631 (CHEMBL494278 | N-(3-((6-chloropyridin-3-yl)methyl)...) Show SMILES Clc1ccc(Cn2ccs\c2=N/C(=O)c2cnccn2)cn1 Show InChI InChI=1S/C14H10ClN5OS/c15-12-2-1-10(7-18-12)9-20-5-6-22-14(20)19-13(21)11-8-16-3-4-17-11/h1-8H,9H2/b19-14-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Displacement of [3H]nicotine from chick alpha4beta2 nAChR				J Med Chem 51: 4213-8 (2008) Article DOI: 10.1021/jm800191a BindingDB Entry DOI: 10.7270/Q2D21XDZ
					More data for this Ligand-Target Pair