BDBM50252793 CHEMBL493060::N-{[1-(3,3-dimethylbutyl)piperidin-4-yl]methyl}-1-(4-fluorophenyl)cyclohexanecarboxamide

SMILES: CC(C)(C)CCN1CCC(CNC(=O)C2(CCCCC2)c2ccc(F)cc2)CC1

InChI Key: InChIKey=MAMUSVZGQPEVAS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50252793   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50252793 (CHEMBL493060 | N-{[1-(3,3-dimethylbutyl)piperidin-...) Show SMILES CC(C)(C)CCN1CCC(CNC(=O)C2(CCCCC2)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C25H39FN2O/c1-24(2,3)15-18-28-16-11-20(12-17-28)19-27-23(29)25(13-5-4-6-14-25)21-7-9-22(26)10-8-21/h7-10,20H,4-6,11-19H2,1-3H3,(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human ERG				J Med Chem 51: 6471-7 (2008) Article DOI: 10.1021/jm800830n BindingDB Entry DOI: 10.7270/Q2N29WT4
					More data for this Ligand-Target Pair
Voltage-gated T-type calcium channel (Homo sapiens (Human))	BDBM50252793 (CHEMBL493060 | N-{[1-(3,3-dimethylbutyl)piperidin-...) Show SMILES CC(C)(C)CCN1CCC(CNC(=O)C2(CCCCC2)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C25H39FN2O/c1-24(2,3)15-18-28-16-11-20(12-17-28)19-27-23(29)25(13-5-4-6-14-25)21-7-9-22(26)10-8-21/h7-10,20H,4-6,11-19H2,1-3H3,(H,27,29)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	99	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of T-type calcium channel alpha1I (unknown origin) by FLIPR				J Med Chem 51: 6471-7 (2008) Article DOI: 10.1021/jm800830n BindingDB Entry DOI: 10.7270/Q2N29WT4
					More data for this Ligand-Target Pair