BDBM50252802 4-(4-Bromophenyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanone Hydrochloride::CHEMBL493658

SMILES: Brc1ccc(CCC(=O)Cn2cncn2)cc1

InChI Key: InChIKey=UBTMSXWHWGTLTL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50252802   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Heme Oxygenase 1 (HO-1) (Rattus norvegicus (rat))	BDBM50252802 (4-(4-Bromophenyl)-1-(1H-1,2,4-triazol-1-yl)-2-buta...) Show SMILES Brc1ccc(CCC(=O)Cn2cncn2)cc1 Show InChI InChI=1S/C12H12BrN3O/c13-11-4-1-10(2-5-11)3-6-12(17)7-16-9-14-8-15-16/h1-2,4-5,8-9H,3,6-7H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Queen's University Curated by ChEMBL					Assay Description Inhibition of HO1 in rat spleen microsomal fraction assessed as carbon monoxide production				J Med Chem 51: 5943-52 (2008) Article DOI: 10.1021/jm800505m BindingDB Entry DOI: 10.7270/Q2RX9BWZ
					More data for this Ligand-Target Pair