BDBM50252833 4-(4-Methoxyphenyl)spiro[chromene-2,4'-piperidine]::CHEMBL495073

SMILES: COc1ccc(cc1)C1=CC2(CCNCC2)Oc2ccccc12

InChI Key: InChIKey=LJIDXOGVDUDHSV-UHFFFAOYSA-N

Data: 1 KI  1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50252833   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50252833 (4-(4-Methoxyphenyl)spiro[chromene-2,4'-piperidine]...) Show SMILES COc1ccc(cc1)C1=CC2(CCNCC2)Oc2ccccc12 |t:9| Show InChI InChI=1S/C20H21NO2/c1-22-16-8-6-15(7-9-16)18-14-20(10-12-21-13-11-20)23-19-5-3-2-4-17(18)19/h2-9,14,21H,10-13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Adolor Corporation Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human delta opioid receptor in CHO cells				J Med Chem 51: 5893-6 (2008) Article DOI: 10.1021/jm8008986 BindingDB Entry DOI: 10.7270/Q26W9C0D
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50252833 (4-(4-Methoxyphenyl)spiro[chromene-2,4'-piperidine]...) Show SMILES COc1ccc(cc1)C1=CC2(CCNCC2)Oc2ccccc12 |t:9| Show InChI InChI=1S/C20H21NO2/c1-22-16-8-6-15(7-9-16)18-14-20(10-12-21-13-11-20)23-19-5-3-2-4-17(18)19/h2-9,14,21H,10-13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	585	n/a	n/a	n/a	n/a	n/a	n/a
Adolor Corporation Curated by ChEMBL					Assay Description Inhibition of human ERG channel in HEK293 cells by voltage-clamp method				J Med Chem 51: 5893-6 (2008) Article DOI: 10.1021/jm8008986 BindingDB Entry DOI: 10.7270/Q26W9C0D
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50252833 (4-(4-Methoxyphenyl)spiro[chromene-2,4'-piperidine]...) Show SMILES COc1ccc(cc1)C1=CC2(CCNCC2)Oc2ccccc12 |t:9| Show InChI InChI=1S/C20H21NO2/c1-22-16-8-6-15(7-9-16)18-14-20(10-12-21-13-11-20)23-19-5-3-2-4-17(18)19/h2-9,14,21H,10-13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	190	n/a	n/a	n/a	n/a
Adolor Corporation Curated by ChEMBL					Assay Description Agonist activity at human delta opioid receptor in CHO cells assessed as stimulation of [35S]GTPgammaS binding				J Med Chem 51: 5893-6 (2008) Article DOI: 10.1021/jm8008986 BindingDB Entry DOI: 10.7270/Q26W9C0D
					More data for this Ligand-Target Pair