BDBM50252890 CHEMBL4064973

SMILES: FS(F)(F)(F)(F)c1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1ccc(Oc2ccccc2)cc1

InChI Key: InChIKey=SUZBAMAJXGRFEB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50252890   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50252890 (CHEMBL4064973) Show SMILES FS(F)(F)(F)(F)c1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C25H20F5NO3S2/c26-36(27,28,29,30)25-17-15-24(16-18-25)35(32,33)31(19-20-7-3-1-4-8-20)21-11-13-23(14-12-21)34-22-9-5-2-6-10-22/h1-18H,19H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Molecular and Cellular Biosciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, 113-0032 Tokyo, Japan. Curated by ChEMBL					Assay Description Antagonist activity at human GRalpha expressed in HEK293 cells assessed as inhibition of dexamethasone-induced response after 24 hrs by luciferase re...				Bioorg Med Chem 25: 3461-3470 (2017) Article DOI: 10.1016/j.bmc.2017.04.032 BindingDB Entry DOI: 10.7270/Q2SF2ZK6
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