BDBM50252975 (2'Z-3'E)-6-Bromoindirubin-3'-[O-(N,N-diethylcarbamyl)-oxime]::CHEMBL494686

SMILES: CCN(CC)C(=O)O\N=C1\C(\Nc2ccccc\12)=C1\C(=O)Nc2cc(Br)ccc12

InChI Key: InChIKey=SLBLIGFYVYSIOX-RCLOYMNUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50252975   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM50252975 ((2'Z-3'E)-6-Bromoindirubin-3'-[O-(N,N-diethylcarba...) Show SMILES CCN(CC)C(=O)O\N=C1\C(\Nc2ccccc\12)=C1\C(=O)Nc2cc(Br)ccc12 Show InChI InChI=1S/C21H19BrN4O3/c1-3-26(4-2)21(28)29-25-18-14-7-5-6-8-15(14)23-19(18)17-13-10-9-12(22)11-16(13)24-20(17)27/h5-11,23H,3-4H2,1-2H3,(H,24,27)/b19-17-,25-18+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens Curated by ChEMBL					Assay Description Inhibition of CDK1/cyclin B				J Med Chem 51: 6421-31 (2008) Article DOI: 10.1021/jm800648y BindingDB Entry DOI: 10.7270/Q22808JG
					More data for this Ligand-Target Pair