BDBM50253181 2-Hydroxy-5-{[(7-{[(7-sulfo(2-naphthyl))amino]carbonylamino}(2-naphthyl))sulfonyl]amino}benzoic Acid::CHEMBL446305

SMILES: OC(=O)c1cc(NS(=O)(=O)c2ccc3ccc(NC(=O)Nc4ccc5ccc(cc5c4)S(=O)(=O)Nc4ccc(O)c(c4)C(O)=O)cc3c2)ccc1O

InChI Key: InChIKey=PBFMJGXKKDPAAX-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50253181   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin receptor (Mus musculus)	BDBM50253181 (2-Hydroxy-5-{[(7-{[(7-sulfo(2-naphthyl))amino]carb...) Show SMILES OC(=O)c1cc(NS(=O)(=O)c2ccc3ccc(NC(=O)Nc4ccc5ccc(cc5c4)S(=O)(=O)Nc4ccc(O)c(c4)C(O)=O)cc3c2)ccc1O Show InChI InChI=1S/C35H26N4O11S2/c40-31-11-7-25(17-29(31)33(42)43)38-51(47,48)27-9-3-19-1-5-23(13-21(19)15-27)36-35(46)37-24-6-2-20-4-10-28(16-22(20)14-24)52(49,50)39-26-8-12-32(41)30(18-26)34(44)45/h1-18,38-41H,(H,42,43)(H,44,45)(H2,36,37,46)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a
Telik, Inc. Curated by ChEMBL					Assay Description Activation of insulin receptor tyrosine kinase in mouse 3T3-L1 cells assessed as increase in 2-deoxy-D-[14C]glucose transport in presence of insulin				J Med Chem 51: 6173-87 (2008) Article DOI: 10.1021/jm800600v BindingDB Entry DOI: 10.7270/Q2ZG6T5K
					More data for this Ligand-Target Pair