BDBM50253197 5-[7-(1-{7-[(3-carboxy-4-chlorophenyl)sulfamoyl]naphthalen-2-yl}-2-methylcarbamimidamido)naphthalene-2-sulfonamido]-2-chlorobenzoic acid::CHEMBL449637

SMILES: CNC(Nc1ccc2ccc(cc2c1)S(=O)(=O)Nc1ccc(Cl)c(c1)C(O)=O)=Nc1ccc2ccc(cc2c1)S(=O)(=O)Nc1ccc(Cl)c(c1)C(O)=O

InChI Key: InChIKey=CIUCBGKVITYNMZ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50253197   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin receptor (Mus musculus)	BDBM50253197 (5-[7-(1-{7-[(3-carboxy-4-chlorophenyl)sulfamoyl]na...) Show SMILES CNC(Nc1ccc2ccc(cc2c1)S(=O)(=O)Nc1ccc(Cl)c(c1)C(O)=O)=Nc1ccc2ccc(cc2c1)S(=O)(=O)Nc1ccc(Cl)c(c1)C(O)=O |w:28.31| Show InChI InChI=1S/C36H27Cl2N5O8S2/c1-39-36(40-24-6-2-20-4-10-28(16-22(20)14-24)52(48,49)42-26-8-12-32(37)30(18-26)34(44)45)41-25-7-3-21-5-11-29(17-23(21)15-25)53(50,51)43-27-9-13-33(38)31(19-27)35(46)47/h2-19,42-43H,1H3,(H,44,45)(H,46,47)(H2,39,40,41)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a
Telik, Inc. Curated by ChEMBL					Assay Description Activation of insulin receptor tyrosine kinase in mouse 3T3-L1 cells assessed as increase in 2-deoxy-D-[14C]glucose transport in presence of insulin				J Med Chem 51: 6173-87 (2008) Article DOI: 10.1021/jm800600v BindingDB Entry DOI: 10.7270/Q2ZG6T5K
					More data for this Ligand-Target Pair