BDBM50253324 5-amino-3-methyl-N2-phenylthiophene-2,4-dicarboxamide::CHEMBL494292

SMILES: Cc1c(sc(N)c1C(N)=O)C(=O)Nc1ccccc1

InChI Key: InChIKey=HUXCUBHSRXMRRQ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50253324   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50253324 (5-amino-3-methyl-N2-phenylthiophene-2,4-dicarboxam...) Show SMILES Cc1c(sc(N)c1C(N)=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C13H13N3O2S/c1-7-9(11(14)17)12(15)19-10(7)13(18)16-8-5-3-2-4-6-8/h2-6H,15H2,1H3,(H2,14,17)(H,16,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.95E+3	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Modulation of human adenosine A1 receptor expressed in CHO-K1 cells assessed as allosteric effect on [125I]ABA dissociation				J Med Chem 51: 6165-72 (2008) Article DOI: 10.1021/jm800557d BindingDB Entry DOI: 10.7270/Q2930T0C
					More data for this Ligand-Target Pair