BDBM50253610 (3-Pyridin-3-yl-naphthalen-2-yl)(4-trifluoromethoxyphenyl)-methanone::CHEMBL492892

SMILES: FC(F)(F)Oc1ccc(cc1)C(=O)c1cc2ccccc2cc1-c1cccnc1

InChI Key: InChIKey=NCJRHWNXUZJLDK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50253610   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM50253610 ((3-Pyridin-3-yl-naphthalen-2-yl)(4-trifluoromethox...) Show SMILES FC(F)(F)Oc1ccc(cc1)C(=O)c1cc2ccccc2cc1-c1cccnc1 Show InChI InChI=1S/C23H14F3NO2/c24-23(25,26)29-19-9-7-15(8-10-19)22(28)21-13-17-5-2-1-4-16(17)12-20(21)18-6-3-11-27-14-18/h1-14H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.13E+4	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human adrenal corticoid CYP11B1 expressed in chinese hamster V79 MZh cells				J Med Chem 51: 6138-49 (2008) Article DOI: 10.1021/jm800683c BindingDB Entry DOI: 10.7270/Q22J6BP4
					More data for this Ligand-Target Pair
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human))	BDBM50253610 ((3-Pyridin-3-yl-naphthalen-2-yl)(4-trifluoromethox...) Show SMILES FC(F)(F)Oc1ccc(cc1)C(=O)c1cc2ccccc2cc1-c1cccnc1 Show InChI InChI=1S/C23H14F3NO2/c24-23(25,26)29-19-9-7-15(8-10-19)22(28)21-13-17-5-2-1-4-16(17)12-20(21)18-6-3-11-27-14-18/h1-14H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cells				J Med Chem 51: 6138-49 (2008) Article DOI: 10.1021/jm800683c BindingDB Entry DOI: 10.7270/Q22J6BP4
					More data for this Ligand-Target Pair