BDBM50253770 CHEMBL518482::[4-(Imidazol-1-yl-phenyl-methyl)-phenyl]-naphthalen-2-yl-amine
SMILES: N(c1ccc(cc1)C(c1ccccc1)n1ccnc1)c1ccc2ccccc2c1
InChI Key: InChIKey=DOYQKEVQXQZQNF-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome CYP26A1 (Homo sapiens (Human)) | BDBM50253770 (CHEMBL518482 | [4-(Imidazol-1-yl-phenyl-methyl)-ph...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Cardiff University Curated by ChEMBL | Assay Description Inhibition of CYP26A1 in human MCF7 cells | Bioorg Med Chem 16: 8301-13 (2008) Article DOI: 10.1016/j.bmc.2007.06.048 BindingDB Entry DOI: 10.7270/Q2M61M5B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome CYP26A1 (Homo sapiens (Human)) | BDBM50253770 (CHEMBL518482 | [4-(Imidazol-1-yl-phenyl-methyl)-ph...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Cardiff University Curated by ChEMBL | Assay Description Inhibition of human CYP26A1 assessed using [11,12-3H]ATRA as substrate by scintillation counting | J Med Chem 54: 6803-11 (2011) Article DOI: 10.1021/jm200695m BindingDB Entry DOI: 10.7270/Q2WM1DSJ | |||||||||||
More data for this Ligand-Target Pair |