BDBM50253785 9,10-Dioxo-9,10-dihydro-anthracene-2,7-dicarboxylic acid bis-{[2-((S)-2,6-diamino-hexanoylamino)-ethyl]-amide}::CHEMBL453264

SMILES: NCCCC[C@H](N)C(=O)NCCNC(=O)c1ccc2C(=O)c3ccc(cc3C(=O)c2c1)C(=O)NCCNC(=O)[C@@H](N)CCCCN

InChI Key: InChIKey=DUOFBYMNESGALY-UIOOFZCWSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50253785   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50253785 (9,10-Dioxo-9,10-dihydro-anthracene-2,7-dicarboxyli...) Show SMILES NCCCC[C@H](N)C(=O)NCCNC(=O)c1ccc2C(=O)c3ccc(cc3C(=O)c2c1)C(=O)NCCNC(=O)[C@@H](N)CCCCN |r| Show InChI InChI=1S/C32H44N8O6/c33-11-3-1-5-25(35)31(45)39-15-13-37-29(43)19-7-9-21-23(17-19)28(42)24-18-20(8-10-22(24)27(21)41)30(44)38-14-16-40-32(46)26(36)6-2-4-12-34/h7-10,17-18,25-26H,1-6,11-16,33-36H2,(H,37,43)(H,38,44)(H,39,45)(H,40,46)/t25-,26-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
University of Padova Curated by ChEMBL					Assay Description Inhibition of telomerase in human JR8 cells by TRAP assay				J Med Chem 51: 5566-74 (2008) Article DOI: 10.1021/jm800160v BindingDB Entry DOI: 10.7270/Q2R78F1Q
					More data for this Ligand-Target Pair
Taq polymerase 1 (Thermus aquaticus)	BDBM50253785 (9,10-Dioxo-9,10-dihydro-anthracene-2,7-dicarboxyli...) Show SMILES NCCCC[C@H](N)C(=O)NCCNC(=O)c1ccc2C(=O)c3ccc(cc3C(=O)c2c1)C(=O)NCCNC(=O)[C@@H](N)CCCCN |r| Show InChI InChI=1S/C32H44N8O6/c33-11-3-1-5-25(35)31(45)39-15-13-37-29(43)19-7-9-21-23(17-19)28(42)24-18-20(8-10-22(24)27(21)41)30(44)38-14-16-40-32(46)26(36)6-2-4-12-34/h7-10,17-18,25-26H,1-6,11-16,33-36H2,(H,37,43)(H,38,44)(H,39,45)(H,40,46)/t25-,26-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a
University of Padova Curated by ChEMBL					Assay Description Inhibition of Taq polymerase				J Med Chem 51: 5566-74 (2008) Article DOI: 10.1021/jm800160v BindingDB Entry DOI: 10.7270/Q2R78F1Q
					More data for this Ligand-Target Pair