BDBM50253787 9,10-Dioxo-9,10-dihydro-anthracene-2,7-dicarboxylic acid bis-{[2-(2-amino-acetylamino)-ethyl]-amide}::CHEMBL516974

SMILES: NCC(=O)NCCNC(=O)c1ccc2C(=O)c3ccc(cc3C(=O)c2c1)C(=O)NCCNC(=O)CN

InChI Key: InChIKey=UACGXWNPXOERHI-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50253787   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50253787 (9,10-Dioxo-9,10-dihydro-anthracene-2,7-dicarboxyli...) Show SMILES NCC(=O)NCCNC(=O)c1ccc2C(=O)c3ccc(cc3C(=O)c2c1)C(=O)NCCNC(=O)CN Show InChI InChI=1S/C24H26N6O6/c25-11-19(31)27-5-7-29-23(35)13-1-3-15-17(9-13)22(34)18-10-14(2-4-16(18)21(15)33)24(36)30-8-6-28-20(32)12-26/h1-4,9-10H,5-8,11-12,25-26H2,(H,27,31)(H,28,32)(H,29,35)(H,30,36)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a
University of Padova Curated by ChEMBL					Assay Description Inhibition of telomerase in human JR8 cells by TRAP assay				J Med Chem 51: 5566-74 (2008) Article DOI: 10.1021/jm800160v BindingDB Entry DOI: 10.7270/Q2R78F1Q
					More data for this Ligand-Target Pair
Taq polymerase 1 (Thermus aquaticus)	BDBM50253787 (9,10-Dioxo-9,10-dihydro-anthracene-2,7-dicarboxyli...) Show SMILES NCC(=O)NCCNC(=O)c1ccc2C(=O)c3ccc(cc3C(=O)c2c1)C(=O)NCCNC(=O)CN Show InChI InChI=1S/C24H26N6O6/c25-11-19(31)27-5-7-29-23(35)13-1-3-15-17(9-13)22(34)18-10-14(2-4-16(18)21(15)33)24(36)30-8-6-28-20(32)12-26/h1-4,9-10H,5-8,11-12,25-26H2,(H,27,31)(H,28,32)(H,29,35)(H,30,36)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a
University of Padova Curated by ChEMBL					Assay Description Inhibition of Taq polymerase				J Med Chem 51: 5566-74 (2008) Article DOI: 10.1021/jm800160v BindingDB Entry DOI: 10.7270/Q2R78F1Q
					More data for this Ligand-Target Pair