BDBM50254082 CHEMBL4073884

SMILES: CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)CNC(=O)[C@H](CC1CCCCC1)NC(=O)[C@H](CS)NC(C)=O)[C@@H](C)CC)C(=O)NCC(N)=O

InChI Key: InChIKey=QVFMMHOEVIUUSW-YYZDLUAOSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50254082   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Atrial natriuretic peptide receptor (Homo sapiens (Human))	BDBM50254082 (CHEMBL4073884) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)CNC(=O)[C@H](CC1CCCCC1)NC(=O)[C@H](CS)NC(C)=O)[C@@H](C)CC)C(=O)NCC(N)=O |r| Show InChI InChI=1S/C48H85N17O13S/c1-6-25(3)38(45(77)57-21-34(49)67)64-42(74)30(16-12-18-55-48(52)53)61-43(75)32(20-37(70)71)63-46(78)39(26(4)7-2)65-41(73)29(15-11-17-54-47(50)51)60-36(69)23-56-35(68)22-58-40(72)31(19-28-13-9-8-10-14-28)62-44(76)33(24-79)59-27(5)66/h25-26,28-33,38-39,79H,6-24H2,1-5H3,(H2,49,67)(H,56,68)(H,57,77)(H,58,72)(H,59,66)(H,60,69)(H,61,75)(H,62,76)(H,63,78)(H,64,74)(H,65,73)(H,70,71)(H4,50,51,54)(H4,52,53,55)/t25-,26-,29-,30-,31-,32-,33-,38-,39-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd Curated by ChEMBL					Assay Description Displacement of [125I]-human ANP from human NPR-1 incubated for 2 hrs by top count method				Bioorg Med Chem Lett 27: 3542-3545 (2017) Article DOI: 10.1016/j.bmcl.2017.05.061 BindingDB Entry DOI: 10.7270/Q2F19241
					More data for this Ligand-Target Pair
Atrial natriuretic peptide receptor 3 (Homo sapiens (Human))	BDBM50254082 (CHEMBL4073884) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)CNC(=O)[C@H](CC1CCCCC1)NC(=O)[C@H](CS)NC(C)=O)[C@@H](C)CC)C(=O)NCC(N)=O |r| Show InChI InChI=1S/C48H85N17O13S/c1-6-25(3)38(45(77)57-21-34(49)67)64-42(74)30(16-12-18-55-48(52)53)61-43(75)32(20-37(70)71)63-46(78)39(26(4)7-2)65-41(73)29(15-11-17-54-47(50)51)60-36(69)23-56-35(68)22-58-40(72)31(19-28-13-9-8-10-14-28)62-44(76)33(24-79)59-27(5)66/h25-26,28-33,38-39,79H,6-24H2,1-5H3,(H2,49,67)(H,56,68)(H,57,77)(H,58,72)(H,59,66)(H,60,69)(H,61,75)(H,62,76)(H,63,78)(H,64,74)(H,65,73)(H,70,71)(H4,50,51,54)(H4,52,53,55)/t25-,26-,29-,30-,31-,32-,33-,38-,39-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd Curated by ChEMBL					Assay Description Displacement of [125I]-human ANP from His-tagged and Fc fragment containing human NPR-3 extracellular domain expressed in FreeStyle 293 cells incubat...				Bioorg Med Chem Lett 27: 3542-3545 (2017) Article DOI: 10.1016/j.bmcl.2017.05.061 BindingDB Entry DOI: 10.7270/Q2F19241
					More data for this Ligand-Target Pair