BindingDB PrimarySearch

BDBM50254365 (+/-)-3-[3-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-(4'-ethoxy-biphenyl-3-sulfonylamino)-3-oxo-propyl]-benzamidine::CHEMBL518179

SMILES: CCOc1ccc(cc1)-c1cccc(c1)S(=O)(=O)NC(Cc1cccc(c1)C(N)=N)C(=O)N1CCC(CCN)CC1

InChI Key: InChIKey=FKQDSIMOEGWTEY-UHFFFAOYSA-N

Data: 5 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50254365
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Hepatocyte growth factor activator/Serine protease hepsin/Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM50254365 ((+/-)-3-[3-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-(4...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Curacyte Discovery GmbH Curated by ChEMBL					Assay Description Inhibition of matriptase (unknown origin)				Bioorg Med Chem Lett 19: 67-73 (2008) Article DOI: 10.1016/j.bmcl.2008.11.019 BindingDB Entry DOI: 10.7270/Q2HH6JXF
Curacyte Discovery GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50254365 ((+/-)-3-[3-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-(4...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Curacyte Discovery GmbH Curated by ChEMBL					Assay Description Inhibition of plasmin (unknown origin)				Bioorg Med Chem Lett 19: 67-73 (2008) Article DOI: 10.1016/j.bmcl.2008.11.019 BindingDB Entry DOI: 10.7270/Q2HH6JXF
Curacyte Discovery GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50254365 ((+/-)-3-[3-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-(4...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Curacyte Discovery GmbH Curated by ChEMBL					Assay Description Inhibition of thrombin (unknown origin)				Bioorg Med Chem Lett 19: 67-73 (2008) Article DOI: 10.1016/j.bmcl.2008.11.019 BindingDB Entry DOI: 10.7270/Q2HH6JXF
Curacyte Discovery GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50254365 ((+/-)-3-[3-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-(4...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	660	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Curacyte Discovery GmbH Curated by ChEMBL					Assay Description Inhibition of factor 10a (unknown origin)				Bioorg Med Chem Lett 19: 67-73 (2008) Article DOI: 10.1016/j.bmcl.2008.11.019 BindingDB Entry DOI: 10.7270/Q2HH6JXF
Curacyte Discovery GmbH Curated by ChEMBL					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50254365 ((+/-)-3-[3-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-(4...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	8.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Curacyte Discovery GmbH Curated by ChEMBL					Assay Description Inhibition of uPA (unknown origin)				Bioorg Med Chem Lett 19: 67-73 (2008) Article DOI: 10.1016/j.bmcl.2008.11.019 BindingDB Entry DOI: 10.7270/Q2HH6JXF
Curacyte Discovery GmbH Curated by ChEMBL					More data for this Ligand-Target Pair