BDBM50254447 1-(4-tert-butylthiazol-2-yl)-3 -(6-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-3,5-dimethyl-2-oxo-1,3-oxazinan-5-yl)urea::1-(4-tert-butylthiazol-2-yl)-3-(6-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-3,5-dimethyl-2-oxo-1,3-oxazinan-5-yl)urea::CHEMBL468695

SMILES: CN1CC(C)(NC(=O)Nc2nc(cs2)C(C)(C)C)C(CN2CCC[C@@H](Cc3ccc(F)cc3)C2)OC1=O

InChI Key: InChIKey=UKCCRJLNYAYHBT-JIUXCQJLSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50254447   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50254447 (1-(4-tert-butylthiazol-2-yl)-3 -(6-(((S)-3-(4-fluo...) Show SMILES CN1CC(C)(NC(=O)Nc2nc(cs2)C(C)(C)C)C(CN2CCC[C@@H](Cc3ccc(F)cc3)C2)OC1=O |r| Show InChI InChI=1S/C27H38FN5O3S/c1-26(2,3)21-16-37-24(29-21)30-23(34)31-27(4)17-32(5)25(35)36-22(27)15-33-12-6-7-19(14-33)13-18-8-10-20(28)11-9-18/h8-11,16,19,22H,6-7,12-15,17H2,1-5H3,(H2,29,30,31,34)/t19-,22?,27?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Binding affinity to CCR3 receptor (unknown origin)				Bioorg Med Chem Lett 19: 96-9 (2008) Article DOI: 10.1016/j.bmcl.2008.11.002 BindingDB Entry DOI: 10.7270/Q2MG7PCW
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50254447 (1-(4-tert-butylthiazol-2-yl)-3 -(6-(((S)-3-(4-fluo...) Show SMILES CN1CC(C)(NC(=O)Nc2nc(cs2)C(C)(C)C)C(CN2CCC[C@@H](Cc3ccc(F)cc3)C2)OC1=O |r| Show InChI InChI=1S/C27H38FN5O3S/c1-26(2,3)21-16-37-24(29-21)30-23(34)31-27(4)17-32(5)25(35)36-22(27)15-33-12-6-7-19(14-33)13-18-8-10-20(28)11-9-18/h8-11,16,19,22H,6-7,12-15,17H2,1-5H3,(H2,29,30,31,34)/t19-,22?,27?/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of CYP2D6 (unknown origin)				Bioorg Med Chem Lett 19: 96-9 (2008) Article DOI: 10.1016/j.bmcl.2008.11.002 BindingDB Entry DOI: 10.7270/Q2MG7PCW
					More data for this Ligand-Target Pair
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50254447 (1-(4-tert-butylthiazol-2-yl)-3 -(6-(((S)-3-(4-fluo...) Show SMILES CN1CC(C)(NC(=O)Nc2nc(cs2)C(C)(C)C)C(CN2CCC[C@@H](Cc3ccc(F)cc3)C2)OC1=O |r| Show InChI InChI=1S/C27H38FN5O3S/c1-26(2,3)21-16-37-24(29-21)30-23(34)31-27(4)17-32(5)25(35)36-22(27)15-33-12-6-7-19(14-33)13-18-8-10-20(28)11-9-18/h8-11,16,19,22H,6-7,12-15,17H2,1-5H3,(H2,29,30,31,34)/t19-,22?,27?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Binding affinity to CCR3 receptor (unknown origin)				Bioorg Med Chem Lett 19: 96-9 (2008) Article DOI: 10.1016/j.bmcl.2008.11.002 BindingDB Entry DOI: 10.7270/Q2MG7PCW
					More data for this Ligand-Target Pair