BDBM50254642 2-(3-(naphthalen-2-ylthio)-1H-indol-4-yloxy)-N-(thiophen-2-ylsulfonyl)acetamide::CHEMBL520290
SMILES: O=C(COc1cccc2[nH]cc(Sc3ccc4ccccc4c3)c12)NS(=O)(=O)c1cccs1
InChI Key: InChIKey=BPWBFGBNTRGBLC-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin E2 receptor (Homo sapiens (Human)) | BDBM50254642 (2-(3-(naphthalen-2-ylthio)-1H-indol-4-yloxy)-N-(th...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry, Inc Curated by ChEMBL | Assay Description Displacement of [3H]PGE2 from human EP3 receptor | Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor (Homo sapiens (Human)) | BDBM50254642 (2-(3-(naphthalen-2-ylthio)-1H-indol-4-yloxy)-N-(th...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 27.5 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry, Inc Curated by ChEMBL | Assay Description Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serum | Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S | |||||||||||
More data for this Ligand-Target Pair |