BDBM50254923 CHEMBL518110::N-(4,5-dichlorothiophen-2-ylsulfonyl)-2-(3-(phenylthio)-1H-indol-4-yloxy)acetamide

SMILES: Clc1cc(sc1Cl)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(Sc3ccccc3)c12

InChI Key: InChIKey=AGISCJRTWDREIL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50254923   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50254923 (CHEMBL518110 | N-(4,5-dichlorothiophen-2-ylsulfony...) Show SMILES Clc1cc(sc1Cl)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(Sc3ccccc3)c12 Show InChI InChI=1S/C20H14Cl2N2O4S3/c21-13-9-18(30-20(13)22)31(26,27)24-17(25)11-28-15-8-4-7-14-19(15)16(10-23-14)29-12-5-2-1-3-6-12/h1-10,23H,11H2,(H,24,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50254923 (CHEMBL518110 | N-(4,5-dichlorothiophen-2-ylsulfony...) Show SMILES Clc1cc(sc1Cl)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(Sc3ccccc3)c12 Show InChI InChI=1S/C20H14Cl2N2O4S3/c21-13-9-18(30-20(13)22)31(26,27)24-17(25)11-28-15-8-4-7-14-19(15)16(10-23-14)29-12-5-2-1-3-6-12/h1-10,23H,11H2,(H,24,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serum				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair