BDBM50255039 1-((5R,6S)-6-(((3-(4-fluorophenyl)propyl)(propyl)amino)methyl)-3-methyl-2-oxo-1,3-oxazinan-5-yl)-3-(4-methylthiazol-2-yl)urea::CHEMBL465943

SMILES: CCCN(CCCc1ccc(F)cc1)C[C@@H]1OC(=O)N(C)C[C@H]1NC(=O)Nc1nc(C)cs1

InChI Key: InChIKey=IETOCDITJQQYHS-UXHICEINSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50255039   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50255039 (1-((5R,6S)-6-(((3-(4-fluorophenyl)propyl)(propyl)a...) Show SMILES CCCN(CCCc1ccc(F)cc1)C[C@@H]1OC(=O)N(C)C[C@H]1NC(=O)Nc1nc(C)cs1 |r| Show InChI InChI=1S/C23H32FN5O3S/c1-4-11-29(12-5-6-17-7-9-18(24)10-8-17)14-20-19(13-28(3)23(31)32-20)26-21(30)27-22-25-16(2)15-33-22/h7-10,15,19-20H,4-6,11-14H2,1-3H3,(H2,25,26,27,30)/t19-,20+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.20	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Binding affinity to CCR3 receptor (unknown origin)				Bioorg Med Chem Lett 19: 96-9 (2008) Article DOI: 10.1016/j.bmcl.2008.11.002 BindingDB Entry DOI: 10.7270/Q2MG7PCW
					More data for this Ligand-Target Pair