BDBM50255042 1-(5-acetyl-4-methylthiazol-2-yl) -3-(6-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-3,5-dimethyl-2-oxo-1,3-oxazinan-5-yl)urea::1-(6-(((S)-3-(4-fluorobenzyl) piperidin-1-yl)methyl)-3,5-dimethyl-2-oxo-1,3-oxazinan-5-yl)-3-(4-methylthiazol-2-yl)urea::1-(6-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-3,5-dimethyl-2-oxo-1,3-oxazinan-5-yl)-3-(4-methylthiazol-2-yl)urea::CHEMBL465272

SMILES: CN1CC(C)(NC(=O)Nc2nc(C)cs2)C(CN2CCC[C@@H](Cc3ccc(F)cc3)C2)OC1=O

InChI Key: InChIKey=PUMZOGIVDCNTEI-ZGIGLSJSSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50255042   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50255042 (1-(5-acetyl-4-methylthiazol-2-yl) -3-(6-(((S)-3-(4...) Show SMILES CN1CC(C)(NC(=O)Nc2nc(C)cs2)C(CN2CCC[C@@H](Cc3ccc(F)cc3)C2)OC1=O |r| Show InChI InChI=1S/C24H32FN5O3S/c1-16-14-34-22(26-16)27-21(31)28-24(2)15-29(3)23(32)33-20(24)13-30-10-4-5-18(12-30)11-17-6-8-19(25)9-7-17/h6-9,14,18,20H,4-5,10-13,15H2,1-3H3,(H2,26,27,28,31)/t18-,20?,24?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.370	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Binding affinity to CCR3 receptor (unknown origin)				Bioorg Med Chem Lett 19: 96-9 (2008) Article DOI: 10.1016/j.bmcl.2008.11.002 BindingDB Entry DOI: 10.7270/Q2MG7PCW
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50255042 (1-(5-acetyl-4-methylthiazol-2-yl) -3-(6-(((S)-3-(4...) Show SMILES CN1CC(C)(NC(=O)Nc2nc(C)cs2)C(CN2CCC[C@@H](Cc3ccc(F)cc3)C2)OC1=O |r| Show InChI InChI=1S/C24H32FN5O3S/c1-16-14-34-22(26-16)27-21(31)28-24(2)15-29(3)23(32)33-20(24)13-30-10-4-5-18(12-30)11-17-6-8-19(25)9-7-17/h6-9,14,18,20H,4-5,10-13,15H2,1-3H3,(H2,26,27,28,31)/t18-,20?,24?/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of CYP2D6 (unknown origin)				Bioorg Med Chem Lett 19: 96-9 (2008) Article DOI: 10.1016/j.bmcl.2008.11.002 BindingDB Entry DOI: 10.7270/Q2MG7PCW
					More data for this Ligand-Target Pair
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50255042 (1-(5-acetyl-4-methylthiazol-2-yl) -3-(6-(((S)-3-(4...) Show SMILES CN1CC(C)(NC(=O)Nc2nc(C)cs2)C(CN2CCC[C@@H](Cc3ccc(F)cc3)C2)OC1=O |r| Show InChI InChI=1S/C24H32FN5O3S/c1-16-14-34-22(26-16)27-21(31)28-24(2)15-29(3)23(32)33-20(24)13-30-10-4-5-18(12-30)11-17-6-8-19(25)9-7-17/h6-9,14,18,20H,4-5,10-13,15H2,1-3H3,(H2,26,27,28,31)/t18-,20?,24?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Binding affinity to CCR3 receptor (unknown origin)				Bioorg Med Chem Lett 19: 96-9 (2008) Article DOI: 10.1016/j.bmcl.2008.11.002 BindingDB Entry DOI: 10.7270/Q2MG7PCW
					More data for this Ligand-Target Pair
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50255042 (1-(5-acetyl-4-methylthiazol-2-yl) -3-(6-(((S)-3-(4...) Show SMILES CN1CC(C)(NC(=O)Nc2nc(C)cs2)C(CN2CCC[C@@H](Cc3ccc(F)cc3)C2)OC1=O |r| Show InChI InChI=1S/C24H32FN5O3S/c1-16-14-34-22(26-16)27-21(31)28-24(2)15-29(3)23(32)33-20(24)13-30-10-4-5-18(12-30)11-17-6-8-19(25)9-7-17/h6-9,14,18,20H,4-5,10-13,15H2,1-3H3,(H2,26,27,28,31)/t18-,20?,24?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Binding affinity to CCR3 receptor (unknown origin)				Bioorg Med Chem Lett 19: 96-9 (2008) Article DOI: 10.1016/j.bmcl.2008.11.002 BindingDB Entry DOI: 10.7270/Q2MG7PCW
					More data for this Ligand-Target Pair