BDBM50255070 1-(5-acetyl-4-methylthiazol-2-yl)-3-(6-(((S)-3-(4-fluorobenzyl)piperidin-1-yl)methyl)-3,5-dimethyl-2-oxo-1,3-oxazinan-5-yl)urea::CHEMBL465291

SMILES: CN1CC(C)(NC(=O)Nc2nc(C)c(s2)C(C)=O)C(CN2CCC[C@@H](Cc3ccc(F)cc3)C2)OC1=O

InChI Key: InChIKey=ZAGLIRVCRPDDPG-SFGGNAAOSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50255070   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50255070 (1-(5-acetyl-4-methylthiazol-2-yl)-3-(6-(((S)-3-(4-...) Show SMILES CN1CC(C)(NC(=O)Nc2nc(C)c(s2)C(C)=O)C(CN2CCC[C@@H](Cc3ccc(F)cc3)C2)OC1=O |r| Show InChI InChI=1S/C26H34FN5O4S/c1-16-22(17(2)33)37-24(28-16)29-23(34)30-26(3)15-31(4)25(35)36-21(26)14-32-11-5-6-19(13-32)12-18-7-9-20(27)10-8-18/h7-10,19,21H,5-6,11-15H2,1-4H3,(H2,28,29,30,34)/t19-,21?,26?/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of CYP2D6 (unknown origin)				Bioorg Med Chem Lett 19: 96-9 (2008) Article DOI: 10.1016/j.bmcl.2008.11.002 BindingDB Entry DOI: 10.7270/Q2MG7PCW
					More data for this Ligand-Target Pair
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50255070 (1-(5-acetyl-4-methylthiazol-2-yl)-3-(6-(((S)-3-(4-...) Show SMILES CN1CC(C)(NC(=O)Nc2nc(C)c(s2)C(C)=O)C(CN2CCC[C@@H](Cc3ccc(F)cc3)C2)OC1=O |r| Show InChI InChI=1S/C26H34FN5O4S/c1-16-22(17(2)33)37-24(28-16)29-23(34)30-26(3)15-31(4)25(35)36-21(26)14-32-11-5-6-19(13-32)12-18-7-9-20(27)10-8-18/h7-10,19,21H,5-6,11-15H2,1-4H3,(H2,28,29,30,34)/t19-,21?,26?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Binding affinity to CCR3 receptor (unknown origin)				Bioorg Med Chem Lett 19: 96-9 (2008) Article DOI: 10.1016/j.bmcl.2008.11.002 BindingDB Entry DOI: 10.7270/Q2MG7PCW
					More data for this Ligand-Target Pair