BDBM50255097 4-((2,3-dihydro-2-oxoquinoxalin-4(1H)-yl)methyl)-N-hydroxybenzamide::CHEMBL481802

SMILES: ONC(=O)c1ccc(CN2CC(=O)Nc3ccccc23)cc1

InChI Key: InChIKey=NMPXWJSMMNHRED-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50255097   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50255097 (4-((2,3-dihydro-2-oxoquinoxalin-4(1H)-yl)methyl)-N...) Show SMILES ONC(=O)c1ccc(CN2CC(=O)Nc3ccccc23)cc1 Show InChI InChI=1S/C16H15N3O3/c20-15-10-19(14-4-2-1-3-13(14)17-15)9-11-5-7-12(8-6-11)16(21)18-22/h1-8,22H,9-10H2,(H,17,20)(H,18,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
MethylGene Inc Curated by ChEMBL					Assay Description Inhibition of human recombinant histone deacetylase 2				Bioorg Med Chem Lett 19: 688-92 (2009) Article DOI: 10.1016/j.bmcl.2008.12.045 BindingDB Entry DOI: 10.7270/Q2G44Q5S
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50255097 (4-((2,3-dihydro-2-oxoquinoxalin-4(1H)-yl)methyl)-N...) Show SMILES ONC(=O)c1ccc(CN2CC(=O)Nc3ccccc23)cc1 Show InChI InChI=1S/C16H15N3O3/c20-15-10-19(14-4-2-1-3-13(14)17-15)9-11-5-7-12(8-6-11)16(21)18-22/h1-8,22H,9-10H2,(H,17,20)(H,18,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
MethylGene Inc Curated by ChEMBL					Assay Description Inhibition of human recombinant histone deacetylase 8				Bioorg Med Chem Lett 19: 688-92 (2009) Article DOI: 10.1016/j.bmcl.2008.12.045 BindingDB Entry DOI: 10.7270/Q2G44Q5S
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM50255097 (4-((2,3-dihydro-2-oxoquinoxalin-4(1H)-yl)methyl)-N...) Show SMILES ONC(=O)c1ccc(CN2CC(=O)Nc3ccccc23)cc1 Show InChI InChI=1S/C16H15N3O3/c20-15-10-19(14-4-2-1-3-13(14)17-15)9-11-5-7-12(8-6-11)16(21)18-22/h1-8,22H,9-10H2,(H,17,20)(H,18,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
MethylGene Inc Curated by ChEMBL					Assay Description Inhibition of human recombinant histone deacetylase 6				Bioorg Med Chem Lett 19: 688-92 (2009) Article DOI: 10.1016/j.bmcl.2008.12.045 BindingDB Entry DOI: 10.7270/Q2G44Q5S
					More data for this Ligand-Target Pair