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SMILES: COc1cc2ncc(C(N)=O)c(Nc3cc(F)ccc3F)c2cc1OC

InChI Key: InChIKey=YMHNYVNOYXPQLO-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50255465   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))		BDBM50255465
PNG
(4-(2,5-difluorophenylamino)-6,7-dimethoxyquinoline...)
Show SMILES COc1cc2ncc(C(N)=O)c(Nc3cc(F)ccc3F)c2cc1OC
Show InChI InChI=1S/C18H15F2N3O3/c1-25-15-6-10-13(7-16(15)26-2)22-8-11(18(21)24)17(10)23-14-5-9(19)3-4-12(14)20/h3-8H,1-2H3,(H2,21,24)(H,22,23)
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antibodypedia
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Similars
Article
PubMed
n/an/a 15n/an/an/an/an/an/a



AstraZeneca R&D Boston

Curated by ChEMBL


Assay Description
Inhibition of His-tagged CSF1R catalytic domain (unknown origin) expressed in baculovirus by HTRF assay

Bioorg Med Chem Lett 19: 697-700 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.046
BindingDB Entry DOI: 10.7270/Q26M36P8
More data for this
Ligand-Target Pair