BDBM50255466 4-(2-fluoro-5-methylphenylamino)-6,7-dimethoxyquinoline-3-carboxamide::CHEMBL521248

SMILES: COc1cc2ncc(C(N)=O)c(Nc3cc(C)ccc3F)c2cc1OC

InChI Key: InChIKey=DRLAQNVAPJIJNS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50255466   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony stimulating factor receptor (Homo sapiens (Human))	BDBM50255466 (4-(2-fluoro-5-methylphenylamino)-6,7-dimethoxyquin...) Show SMILES COc1cc2ncc(C(N)=O)c(Nc3cc(C)ccc3F)c2cc1OC Show InChI InChI=1S/C19H18FN3O3/c1-10-4-5-13(20)15(6-10)23-18-11-7-16(25-2)17(26-3)8-14(11)22-9-12(18)19(21)24/h4-9H,1-3H3,(H2,21,24)(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Boston Curated by ChEMBL					Assay Description Inhibition of His-tagged CSF1R catalytic domain (unknown origin) expressed in baculovirus by HTRF assay				Bioorg Med Chem Lett 19: 697-700 (2009) Article DOI: 10.1016/j.bmcl.2008.12.046 BindingDB Entry DOI: 10.7270/Q26M36P8
					More data for this Ligand-Target Pair