null

SMILES: CC(C)(C)c1ccc(NC(=O)N2CCC3(CN(C3=O)c3ccccc3)CC2)cc1

InChI Key: InChIKey=MYYKJFAAUPAHBF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50255471   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50255471 (CHEMBL518965 | N-(4-tert-butylphenyl)-1-oxo-2-phen...) Show SMILES CC(C)(C)c1ccc(NC(=O)N2CCC3(CN(C3=O)c3ccccc3)CC2)cc1 Show InChI InChI=1S/C24H29N3O2/c1-23(2,3)18-9-11-19(12-10-18)25-22(29)26-15-13-24(14-16-26)17-27(21(24)28)20-7-5-4-6-8-20/h4-12H,13-17H2,1-3H3,(H,25,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Antagonist activity at TRPV1 expressed in HEK293 cells assessed as inhibition of PMA-induced activation by FLIPR assay				Bioorg Med Chem Lett 19: 783-7 (2009) Article DOI: 10.1016/j.bmcl.2008.12.024 BindingDB Entry DOI: 10.7270/Q2F47P1D
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50255471 (CHEMBL518965 | N-(4-tert-butylphenyl)-1-oxo-2-phen...) Show SMILES CC(C)(C)c1ccc(NC(=O)N2CCC3(CN(C3=O)c3ccccc3)CC2)cc1 Show InChI InChI=1S/C24H29N3O2/c1-23(2,3)18-9-11-19(12-10-18)25-22(29)26-15-13-24(14-16-26)17-27(21(24)28)20-7-5-4-6-8-20/h4-12H,13-17H2,1-3H3,(H,25,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Antagonist activity at TRPV1 (unknown origin) expressed in HEK293 cells assessed as inhibition of capsaicin-induced activation by FLIPR assay				Bioorg Med Chem Lett 19: 783-7 (2009) Article DOI: 10.1016/j.bmcl.2008.12.024 BindingDB Entry DOI: 10.7270/Q2F47P1D
					More data for this Ligand-Target Pair