BDBM50255502 2-(2-(4-phenyl-5,6-dihydropyridin-1(2H)-yl)ethyl)phenanthridin-6(5H)-one::CHEMBL480234

SMILES: O=c1[nH]c2ccc(CCN3CCC(=CC3)c3ccccc3)cc2c2ccccc12

InChI Key: InChIKey=WIWNWYBDOLZLDF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50255502   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50255502 (2-(2-(4-phenyl-5,6-dihydropyridin-1(2H)-yl)ethyl)p...) Show SMILES O=c1[nH]c2ccc(CCN3CCC(=CC3)c3ccccc3)cc2c2ccccc12 |c:12| Show InChI InChI=1S/C26H24N2O/c29-26-23-9-5-4-8-22(23)24-18-19(10-11-25(24)27-26)12-15-28-16-13-21(14-17-28)20-6-2-1-3-7-20/h1-11,13,18H,12,14-17H2,(H,27,29)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Huazhong University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of human recombinant PARP1				J Med Chem 52: 718-25 (2009) Article DOI: 10.1021/jm800902t BindingDB Entry DOI: 10.7270/Q2C53KPW
					More data for this Ligand-Target Pair