BDBM50255630 5-methyl-N-(3-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)phenyl)-2-phenylthiazole-4-carboxamide::CHEMBL479861
SMILES: Cc1sc(nc1C(=O)Nc1cccc(Cc2n[nH]c(=O)c3ccccc23)c1)-c1ccccc1
InChI Key: InChIKey=RQTHPFWQOJVNOJ-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human)) | BDBM50255630 (5-methyl-N-(3-((4-oxo-3,4-dihydrophthalazin-1-yl)m...) | PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Huazhong University of Science and Technology Curated by ChEMBL | Assay Description Inhibition of human recombinant PARP1 | J Med Chem 52: 718-25 (2009) Article DOI: 10.1021/jm800902t BindingDB Entry DOI: 10.7270/Q2C53KPW | |||||||||||
More data for this Ligand-Target Pair |