BDBM50255792 1-p-Tolyl-8,9-dihydro-7H-2,7,9a-triaza-benzo[cd]azulen-6-one::CHEMBL481204

SMILES: Cc1ccc(cc1)-c1nc2cccc3C(=O)NCCn1c23

InChI Key: InChIKey=WQKOQOZXZQJNRC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50255792   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50255792 (1-p-Tolyl-8,9-dihydro-7H-2,7,9a-triaza-benzo[cd]az...) Show SMILES Cc1ccc(cc1)-c1nc2cccc3C(=O)NCCn1c23 Show InChI InChI=1S/C17H15N3O/c1-11-5-7-12(8-6-11)16-19-14-4-2-3-13-15(14)20(16)10-9-18-17(13)21/h2-8H,9-10H2,1H3,(H,18,21)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	111	n/a	n/a	n/a	n/a	n/a	n/a
Huazhong University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of human recombinant PARP1				J Med Chem 52: 718-25 (2009) Article DOI: 10.1021/jm800902t BindingDB Entry DOI: 10.7270/Q2C53KPW
					More data for this Ligand-Target Pair