BDBM50256158 CHEMBL519950::N-((5-chloro-8-hydroxyquinolin-7-yl)(2-nitrophenyl)methyl)-2-phenoxyacetamide

SMILES: Oc1c(cc(Cl)c2cccnc12)C(NC(=O)COc1ccccc1)c1ccccc1[N+]([O-])=O

InChI Key: InChIKey=SCOSGHHZRROAJY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50256158   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5) (Homo sapiens (Human))	BDBM50256158 (CHEMBL519950 | N-((5-chloro-8-hydroxyquinolin-7-yl...) Show SMILES Oc1c(cc(Cl)c2cccnc12)C(NC(=O)COc1ccccc1)c1ccccc1[N+]([O-])=O Show InChI InChI=1S/C24H18ClN3O5/c25-19-13-18(24(30)23-16(19)10-6-12-26-23)22(17-9-4-5-11-20(17)28(31)32)27-21(29)14-33-15-7-2-1-3-8-15/h1-13,22,30H,14H2,(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.21E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of ADAMTS5 by FRET assay				Bioorg Med Chem Lett 18: 6454-7 (2008) Article DOI: 10.1016/j.bmcl.2008.10.065 BindingDB Entry DOI: 10.7270/Q25H7G34
					More data for this Ligand-Target Pair