US11028090, Example 493 4-(7- imidazole- 1-yl-1- methyl- [1,2,4]triazolo[4,3- a]quinoxaline- 4-ylamino)- butyl]- carbamic acid isobutylester

SMILES: CC(C)COC(=O)NCCCCNc1nc2cc(ccc2n2c(C)nnc12)-n1ccnc1

InChI Key: InChIKey=QKQHDZIZNMWRFA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 502566   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502566 (4-(7- imidazole- 1-yl-1- methyl- [1,2,4]triazolo[4...) Show SMILES CC(C)COC(=O)NCCCCNc1nc2cc(ccc2n2c(C)nnc12)-n1ccnc1 Show InChI InChI=1S/C22H28N8O2/c1-15(2)13-32-22(31)25-9-5-4-8-24-20-21-28-27-16(3)30(21)19-7-6-17(12-18(19)26-20)29-11-10-23-14-29/h6-7,10-12,14-15H,4-5,8-9,13H2,1-3H3,(H,24,26)(H,25,31)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021)
					More data for this Ligand-Target Pair