BDBM50256958 3-Isopropoxy-5-[2-(methylsulfonyl)phenoxy]-N-(4-methyl-1,3-thiazol-2-yl)benzamide::CHEMBL475057

SMILES: CC(C)Oc1cc(Oc2ccccc2S(C)(=O)=O)cc(c1)C(=O)Nc1nc(C)cs1

InChI Key: InChIKey=HEURRWQIVIAYGR-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50256958   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucokinase/Glucokinase regulatory protein (Homo sapiens (Human))	BDBM50256958 (3-Isopropoxy-5-[2-(methylsulfonyl)phenoxy]-N-(4-me...) Show SMILES CC(C)Oc1cc(Oc2ccccc2S(C)(=O)=O)cc(c1)C(=O)Nc1nc(C)cs1 Show InChI InChI=1S/C21H22N2O5S2/c1-13(2)27-16-9-15(20(24)23-21-22-14(3)12-29-21)10-17(11-16)28-18-7-5-6-8-19(18)30(4,25)26/h5-13H,1-4H3,(H,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	440	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Activation of flag-tagged human recombinant liver glucokinase expressed in Escherichia coli by glucose-6-phosphate dehydrogenase coupled continuous s...				Bioorg Med Chem 17: 2733-43 (2009) Article DOI: 10.1016/j.bmc.2009.02.038 BindingDB Entry DOI: 10.7270/Q2NV9J4Z
					More data for this Ligand-Target Pair
Glucokinase/Glucokinase regulatory protein (Homo sapiens (Human))	BDBM50256958 (3-Isopropoxy-5-[2-(methylsulfonyl)phenoxy]-N-(4-me...) Show SMILES CC(C)Oc1cc(Oc2ccccc2S(C)(=O)=O)cc(c1)C(=O)Nc1nc(C)cs1 Show InChI InChI=1S/C21H22N2O5S2/c1-13(2)27-16-9-15(20(24)23-21-22-14(3)12-29-21)10-17(11-16)28-18-7-5-6-8-19(18)30(4,25)26/h5-13H,1-4H3,(H,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Activation of flag-tagged human recombinant liver glucokinase expressed in Escherichia coli by glucose-6-phosphate dehydrogenase coupled continuous s...				Bioorg Med Chem 17: 2733-43 (2009) Article DOI: 10.1016/j.bmc.2009.02.038 BindingDB Entry DOI: 10.7270/Q2NV9J4Z
					More data for this Ligand-Target Pair