null

SMILES: Cc1ccc(NC(=O)c2ccc(cc2)C(=O)Nc2ccccc2N)cc1Nc1ncc(cn1)-c1cccnc1

InChI Key: InChIKey=JUZVLELTCCUPPD-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50256976   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50256976 (CHEMBL475820 | N1-(2-aminophenyl)-N4-(4-methyl-3-(...) Show SMILES Cc1ccc(NC(=O)c2ccc(cc2)C(=O)Nc2ccccc2N)cc1Nc1ncc(cn1)-c1cccnc1 Show InChI InChI=1S/C30H25N7O2/c1-19-8-13-24(15-27(19)37-30-33-17-23(18-34-30)22-5-4-14-32-16-22)35-28(38)20-9-11-21(12-10-20)29(39)36-26-7-3-2-6-25(26)31/h2-18H,31H2,1H3,(H,35,38)(H,36,39)(H,33,34,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 expressed in HEK293 cells				J Med Chem 52: 2265-79 (2009) Article DOI: 10.1021/jm800988r BindingDB Entry DOI: 10.7270/Q2NS0TSP
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50256976 (CHEMBL475820 | N1-(2-aminophenyl)-N4-(4-methyl-3-(...) Show SMILES Cc1ccc(NC(=O)c2ccc(cc2)C(=O)Nc2ccccc2N)cc1Nc1ncc(cn1)-c1cccnc1 Show InChI InChI=1S/C30H25N7O2/c1-19-8-13-24(15-27(19)37-30-33-17-23(18-34-30)22-5-4-14-32-16-22)35-28(38)20-9-11-21(12-10-20)29(39)36-26-7-3-2-6-25(26)31/h2-18H,31H2,1H3,(H,35,38)(H,36,39)(H,33,34,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) by liquid scintillation counting				J Med Chem 52: 2265-79 (2009) Article DOI: 10.1021/jm800988r BindingDB Entry DOI: 10.7270/Q2NS0TSP
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50256976 (CHEMBL475820 | N1-(2-aminophenyl)-N4-(4-methyl-3-(...) Show SMILES Cc1ccc(NC(=O)c2ccc(cc2)C(=O)Nc2ccccc2N)cc1Nc1ncc(cn1)-c1cccnc1 Show InChI InChI=1S/C30H25N7O2/c1-19-8-13-24(15-27(19)37-30-33-17-23(18-34-30)22-5-4-14-32-16-22)35-28(38)20-9-11-21(12-10-20)29(39)36-26-7-3-2-6-25(26)31/h2-18H,31H2,1H3,(H,35,38)(H,36,39)(H,33,34,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Inhibition of wild-type c-Abl (unknown origin) by liquid scintillation counting				J Med Chem 52: 2265-79 (2009) Article DOI: 10.1021/jm800988r BindingDB Entry DOI: 10.7270/Q2NS0TSP
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50256976 (CHEMBL475820 | N1-(2-aminophenyl)-N4-(4-methyl-3-(...) Show SMILES Cc1ccc(NC(=O)c2ccc(cc2)C(=O)Nc2ccccc2N)cc1Nc1ncc(cn1)-c1cccnc1 Show InChI InChI=1S/C30H25N7O2/c1-19-8-13-24(15-27(19)37-30-33-17-23(18-34-30)22-5-4-14-32-16-22)35-28(38)20-9-11-21(12-10-20)29(39)36-26-7-3-2-6-25(26)31/h2-18H,31H2,1H3,(H,35,38)(H,36,39)(H,33,34,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta (unknown origin) by liquid scintillation counting				J Med Chem 52: 2265-79 (2009) Article DOI: 10.1021/jm800988r BindingDB Entry DOI: 10.7270/Q2NS0TSP
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50256976 (CHEMBL475820 | N1-(2-aminophenyl)-N4-(4-methyl-3-(...) Show SMILES Cc1ccc(NC(=O)c2ccc(cc2)C(=O)Nc2ccccc2N)cc1Nc1ncc(cn1)-c1cccnc1 Show InChI InChI=1S/C30H25N7O2/c1-19-8-13-24(15-27(19)37-30-33-17-23(18-34-30)22-5-4-14-32-16-22)35-28(38)20-9-11-21(12-10-20)29(39)36-26-7-3-2-6-25(26)31/h2-18H,31H2,1H3,(H,35,38)(H,36,39)(H,33,34,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC6 expressed in HEK293 cells				J Med Chem 52: 2265-79 (2009) Article DOI: 10.1021/jm800988r BindingDB Entry DOI: 10.7270/Q2NS0TSP
					More data for this Ligand-Target Pair