BDBM50257361 2-{1-[3-(6-Benzoyl-1-propyl-naphthalen-2-yloxy)-propyl]-1,2,3,4-tetrahydro-quinolin-5-yloxy}-2-methyl-propionic acid::CHEMBL448996

SMILES: CCCc1c(OCCCN2CCCc3c(OC(C)(C)C(O)=O)cccc23)ccc2cc(ccc12)C(=O)c1ccccc1

InChI Key: InChIKey=ITOWIDRWCNSSCV-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50257361   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50257361 (2-{1-[3-(6-Benzoyl-1-propyl-naphthalen-2-yloxy)-pr...) Show SMILES CCCc1c(OCCCN2CCCc3c(OC(C)(C)C(O)=O)cccc23)ccc2cc(ccc12)C(=O)c1ccccc1 Show InChI InChI=1S/C36H39NO5/c1-4-11-29-28-19-17-27(34(38)25-12-6-5-7-13-25)24-26(28)18-20-32(29)41-23-10-22-37-21-9-14-30-31(37)15-8-16-33(30)42-36(2,3)35(39)40/h5-8,12-13,15-20,24H,4,9-11,14,21-23H2,1-3H3,(H,39,40)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	120	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Agonist activity at human PPARalpha receptor by cell based transactivation assay				J Med Chem 52: 2618-22 (2009) Article DOI: 10.1021/jm801594x BindingDB Entry DOI: 10.7270/Q2SJ1KGZ
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50257361 (2-{1-[3-(6-Benzoyl-1-propyl-naphthalen-2-yloxy)-pr...) Show SMILES CCCc1c(OCCCN2CCCc3c(OC(C)(C)C(O)=O)cccc23)ccc2cc(ccc12)C(=O)c1ccccc1 Show InChI InChI=1S/C36H39NO5/c1-4-11-29-28-19-17-27(34(38)25-12-6-5-7-13-25)24-26(28)18-20-32(29)41-23-10-22-37-21-9-14-30-31(37)15-8-16-33(30)42-36(2,3)35(39)40/h5-8,12-13,15-20,24H,4,9-11,14,21-23H2,1-3H3,(H,39,40)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Agonist activity at human PPARdelta receptor by cell based transactivation assay				J Med Chem 52: 2618-22 (2009) Article DOI: 10.1021/jm801594x BindingDB Entry DOI: 10.7270/Q2SJ1KGZ
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50257361 (2-{1-[3-(6-Benzoyl-1-propyl-naphthalen-2-yloxy)-pr...) Show SMILES CCCc1c(OCCCN2CCCc3c(OC(C)(C)C(O)=O)cccc23)ccc2cc(ccc12)C(=O)c1ccccc1 Show InChI InChI=1S/C36H39NO5/c1-4-11-29-28-19-17-27(34(38)25-12-6-5-7-13-25)24-26(28)18-20-32(29)41-23-10-22-37-21-9-14-30-31(37)15-8-16-33(30)42-36(2,3)35(39)40/h5-8,12-13,15-20,24H,4,9-11,14,21-23H2,1-3H3,(H,39,40)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma receptor by cell based transactivation assay				J Med Chem 52: 2618-22 (2009) Article DOI: 10.1021/jm801594x BindingDB Entry DOI: 10.7270/Q2SJ1KGZ
					More data for this Ligand-Target Pair