BDBM50257397 CHEMBL510383::trans-[2-(3-Hydroxyphenyl)cyclopropyl]methylamine Hydrochloride

SMILES: NC[C@H]1C[C@@H]1c1cccc(O)c1

InChI Key: InChIKey=NZTVPKOZOOULAP-PSASIEDQSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50257397   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50257397 (CHEMBL510383 | trans-[2-(3-Hydroxyphenyl)cycloprop...) Show SMILES NC[C@H]1C[C@@H]1c1cccc(O)c1 |r| Show InChI InChI=1S/C10H13NO/c11-6-8-5-10(8)7-2-1-3-9(12)4-7/h1-4,8,10,12H,5-6,11H2/t8-,10-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.30	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at human 5HT2C receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay				J Med Chem 52: 1885-902 (2009) Article DOI: 10.1021/jm801354e BindingDB Entry DOI: 10.7270/Q2DB81R3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50257397 (CHEMBL510383 | trans-[2-(3-Hydroxyphenyl)cycloprop...) Show SMILES NC[C@H]1C[C@@H]1c1cccc(O)c1 |r| Show InChI InChI=1S/C10H13NO/c11-6-8-5-10(8)7-2-1-3-9(12)4-7/h1-4,8,10,12H,5-6,11H2/t8-,10-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.5	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at human 5HT2B receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay				J Med Chem 52: 1885-902 (2009) Article DOI: 10.1021/jm801354e BindingDB Entry DOI: 10.7270/Q2DB81R3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50257397 (CHEMBL510383 | trans-[2-(3-Hydroxyphenyl)cycloprop...) Show SMILES NC[C@H]1C[C@@H]1c1cccc(O)c1 |r| Show InChI InChI=1S/C10H13NO/c11-6-8-5-10(8)7-2-1-3-9(12)4-7/h1-4,8,10,12H,5-6,11H2/t8-,10-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	247	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at human 5HT2A receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay				J Med Chem 52: 1885-902 (2009) Article DOI: 10.1021/jm801354e BindingDB Entry DOI: 10.7270/Q2DB81R3
					More data for this Ligand-Target Pair