BDBM50257435 (S)-1-((S)-2-cyanopyrrolidin-1-yl)-1,5-dioxo-5-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)pentan-2-aminium 2,2,2-trifluoroacetate::CHEMBL492733

SMILES: [NH3+][C@@H](CCC(=O)N1CCn2c(C1)nnc2C(F)(F)F)C(=O)N1CCC[C@H]1C#N

InChI Key: InChIKey=UHGFPMQZPZHCRI-QWRGUYRKSA-O

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50257435   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50257435 ((S)-1-((S)-2-cyanopyrrolidin-1-yl)-1,5-dioxo-5-(3-...) Show SMILES [NH3+][C@@H](CCC(=O)N1CCn2c(C1)nnc2C(F)(F)F)C(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C16H20F3N7O2/c17-16(18,19)15-23-22-12-9-24(6-7-26(12)15)13(27)4-3-11(21)14(28)25-5-1-2-10(25)8-20/h10-11H,1-7,9,21H2/p+1/t10-,11-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of DPP4 (unknown origin)				Bioorg Med Chem Lett 19: 1908-12 (2009) Article DOI: 10.1016/j.bmcl.2009.02.061 BindingDB Entry DOI: 10.7270/Q2348K74
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human))	BDBM50257435 ((S)-1-((S)-2-cyanopyrrolidin-1-yl)-1,5-dioxo-5-(3-...) Show SMILES [NH3+][C@@H](CCC(=O)N1CCn2c(C1)nnc2C(F)(F)F)C(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C16H20F3N7O2/c17-16(18,19)15-23-22-12-9-24(6-7-26(12)15)13(27)4-3-11(21)14(28)25-5-1-2-10(25)8-20/h10-11H,1-7,9,21H2/p+1/t10-,11-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of DPP2 (unknown origin)				Bioorg Med Chem Lett 19: 1908-12 (2009) Article DOI: 10.1016/j.bmcl.2009.02.061 BindingDB Entry DOI: 10.7270/Q2348K74
					More data for this Ligand-Target Pair
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50257435 ((S)-1-((S)-2-cyanopyrrolidin-1-yl)-1,5-dioxo-5-(3-...) Show SMILES [NH3+][C@@H](CCC(=O)N1CCn2c(C1)nnc2C(F)(F)F)C(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C16H20F3N7O2/c17-16(18,19)15-23-22-12-9-24(6-7-26(12)15)13(27)4-3-11(21)14(28)25-5-1-2-10(25)8-20/h10-11H,1-7,9,21H2/p+1/t10-,11-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of DPP8 (unknown origin)				Bioorg Med Chem Lett 19: 1908-12 (2009) Article DOI: 10.1016/j.bmcl.2009.02.061 BindingDB Entry DOI: 10.7270/Q2348K74
					More data for this Ligand-Target Pair