BDBM50257646 6-benzyl-8-(4-methoxybenzyl)-6,8-diazabicyclo[3.2.2]nonan-2-one::CHEMBL492736

SMILES: COc1ccc(CN2CC3CCC(=O)C2CN3Cc2ccccc2)cc1

InChI Key: InChIKey=TZVJOPQQTYXFME-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50257646   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50257646 (6-benzyl-8-(4-methoxybenzyl)-6,8-diazabicyclo[3.2....) Show SMILES COc1ccc(CN2CC3CCC(=O)C2CN3Cc2ccccc2)cc1 |TLB:13:12:16.15:8.7,6:7:16.15:10.11.12,THB:17:16:8.7:10.11.12| Show InChI InChI=1S/C22H26N2O2/c1-26-20-10-7-18(8-11-20)14-24-15-19-9-12-22(25)21(24)16-23(19)13-17-5-3-2-4-6-17/h2-8,10-11,19,21H,9,12-16H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut fur Pharmazeutische und Medizinische Chemie der Westfalischen Wilhelms-Universitat Munster Curated by ChEMBL					Assay Description Binding affinity to sigma 1 receptor (unknown origin)				J Med Chem 52: 2126-37 (2009) Article DOI: 10.1021/jm801522j BindingDB Entry DOI: 10.7270/Q2ZG6S4Q
					More data for this Ligand-Target Pair