Found 6 hits for monomerid = 50257663 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Hepatocyte growth factor activator/Serine protease hepsin/Suppressor of tumorigenicity 14 protein
(Homo sapiens (Human)) | BDBM50257663
((S)-3-amino-N-(3-(N-(3-(3-carbamimidoylphenyl)-1-o...)Show SMILES NCCC(=O)Nc1cccc(c1)S(=O)(=O)N[C@@H](Cc1cccc(c1)C(N)=N)C(=O)N1CCCCC1 |r| Show InChI InChI=1S/C24H32N6O4S/c25-11-10-22(31)28-19-8-5-9-20(16-19)35(33,34)29-21(24(32)30-12-2-1-3-13-30)15-17-6-4-7-18(14-17)23(26)27/h4-9,14,16,21,29H,1-3,10-13,15,25H2,(H3,26,27)(H,28,31)/t21-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| US Patent
| 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Medicines Company (Leipzig) GmbH
US Patent
| Assay Description Inhibition assay using matriptase enzyme |
US Patent US8569313 (2013)
BindingDB Entry DOI: 10.7270/Q2639ND5 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor activator/Serine protease hepsin/Suppressor of tumorigenicity 14 protein
(Homo sapiens (Human)) | BDBM50257663
((S)-3-amino-N-(3-(N-(3-(3-carbamimidoylphenyl)-1-o...)Show SMILES NCCC(=O)Nc1cccc(c1)S(=O)(=O)N[C@@H](Cc1cccc(c1)C(N)=N)C(=O)N1CCCCC1 |r| Show InChI InChI=1S/C24H32N6O4S/c25-11-10-22(31)28-19-8-5-9-20(16-19)35(33,34)29-21(24(32)30-12-2-1-3-13-30)15-17-6-4-7-18(14-17)23(26)27/h4-9,14,16,21,29H,1-3,10-13,15,25H2,(H3,26,27)(H,28,31)/t21-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 33 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Medicines Company (Leipzig) GmbH
Curated by ChEMBL
| Assay Description Inhibition of matriptase (unknown origin) |
Bioorg Med Chem Lett 19: 1960-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.047 BindingDB Entry DOI: 10.7270/Q2J96681 |
More data for this Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50257663
((S)-3-amino-N-(3-(N-(3-(3-carbamimidoylphenyl)-1-o...)Show SMILES NCCC(=O)Nc1cccc(c1)S(=O)(=O)N[C@@H](Cc1cccc(c1)C(N)=N)C(=O)N1CCCCC1 |r| Show InChI InChI=1S/C24H32N6O4S/c25-11-10-22(31)28-19-8-5-9-20(16-19)35(33,34)29-21(24(32)30-12-2-1-3-13-30)15-17-6-4-7-18(14-17)23(26)27/h4-9,14,16,21,29H,1-3,10-13,15,25H2,(H3,26,27)(H,28,31)/t21-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 270 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Medicines Company (Leipzig) GmbH
Curated by ChEMBL
| Assay Description Inhibition of thrombin (unknown origin) |
Bioorg Med Chem Lett 19: 1960-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.047 BindingDB Entry DOI: 10.7270/Q2J96681 |
More data for this Ligand-Target Pair | |
Urokinase-type plasminogen activator
(Homo sapiens (Human)) | BDBM50257663
((S)-3-amino-N-(3-(N-(3-(3-carbamimidoylphenyl)-1-o...)Show SMILES NCCC(=O)Nc1cccc(c1)S(=O)(=O)N[C@@H](Cc1cccc(c1)C(N)=N)C(=O)N1CCCCC1 |r| Show InChI InChI=1S/C24H32N6O4S/c25-11-10-22(31)28-19-8-5-9-20(16-19)35(33,34)29-21(24(32)30-12-2-1-3-13-30)15-17-6-4-7-18(14-17)23(26)27/h4-9,14,16,21,29H,1-3,10-13,15,25H2,(H3,26,27)(H,28,31)/t21-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Medicines Company (Leipzig) GmbH
Curated by ChEMBL
| Assay Description Inhibition of uPA (unknown origin) |
Bioorg Med Chem Lett 19: 1960-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.047 BindingDB Entry DOI: 10.7270/Q2J96681 |
More data for this Ligand-Target Pair | |
Plasminogen
(Homo sapiens (Human)) | BDBM50257663
((S)-3-amino-N-(3-(N-(3-(3-carbamimidoylphenyl)-1-o...)Show SMILES NCCC(=O)Nc1cccc(c1)S(=O)(=O)N[C@@H](Cc1cccc(c1)C(N)=N)C(=O)N1CCCCC1 |r| Show InChI InChI=1S/C24H32N6O4S/c25-11-10-22(31)28-19-8-5-9-20(16-19)35(33,34)29-21(24(32)30-12-2-1-3-13-30)15-17-6-4-7-18(14-17)23(26)27/h4-9,14,16,21,29H,1-3,10-13,15,25H2,(H3,26,27)(H,28,31)/t21-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Medicines Company (Leipzig) GmbH
Curated by ChEMBL
| Assay Description Inhibition of plasmin (unknown origin) |
Bioorg Med Chem Lett 19: 1960-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.047 BindingDB Entry DOI: 10.7270/Q2J96681 |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50257663
((S)-3-amino-N-(3-(N-(3-(3-carbamimidoylphenyl)-1-o...)Show SMILES NCCC(=O)Nc1cccc(c1)S(=O)(=O)N[C@@H](Cc1cccc(c1)C(N)=N)C(=O)N1CCCCC1 |r| Show InChI InChI=1S/C24H32N6O4S/c25-11-10-22(31)28-19-8-5-9-20(16-19)35(33,34)29-21(24(32)30-12-2-1-3-13-30)15-17-6-4-7-18(14-17)23(26)27/h4-9,14,16,21,29H,1-3,10-13,15,25H2,(H3,26,27)(H,28,31)/t21-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Medicines Company (Leipzig) GmbH
Curated by ChEMBL
| Assay Description Inhibition of factor 10a (unknown origin) |
Bioorg Med Chem Lett 19: 1960-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.047 BindingDB Entry DOI: 10.7270/Q2J96681 |
More data for this Ligand-Target Pair | |