BDBM50257714 CHEMBL4071769

SMILES: OCCCCCn1c(C(=O)NC23CC4CC(CC(C4)C2)C3)c(F)c2ccccc12

InChI Key: InChIKey=LZIQMZLSUFZQMT-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50257714   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50257714 (CHEMBL4071769) Show SMILES OCCCCCn1c(C(=O)NC23CC4CC(CC(C4)C2)C3)c(F)c2ccccc12 |THB:16:15:12:18.17.19,16:17:14.15.20:12,19:17:14:20.11.12,19:11:14:18.16.17| Show InChI InChI=1S/C24H31FN2O2/c25-21-19-6-2-3-7-20(19)27(8-4-1-5-9-28)22(21)23(29)26-24-13-16-10-17(14-24)12-18(11-16)15-24/h2-3,6-7,16-18,28H,1,4-5,8-15H2,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	610	n/a	n/a	n/a	n/a
Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University , 3663 North Zhongshan Road, Shang Curated by ChEMBL					Assay Description Antagonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of CP55940-induced Ca2+ flux preincubated for 10 mins followe...				J Med Chem 60: 7067-7083 (2017) Article DOI: 10.1021/acs.jmedchem.7b00724 BindingDB Entry DOI: 10.7270/Q20K2C17
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