BDBM50257744 CHEMBL4078172

SMILES: FC(F)(F)CCCn1c(cc2ccccc12)C(=O)NC12CC3CC(CC(C3)C1)C2

InChI Key: InChIKey=OBXVPQXCOGOHER-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50257744   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50257744 (CHEMBL4078172) Show SMILES FC(F)(F)CCCn1c(cc2ccccc12)C(=O)NC12CC3CC(CC(C3)C1)C2 |THB:24:23:20:26.25.27,24:25:22.23.28:20,27:25:22:28.19.20,27:19:22:26.24.25| Show InChI InChI=1S/C23H27F3N2O/c24-23(25,26)6-3-7-28-19-5-2-1-4-18(19)11-20(28)21(29)27-22-12-15-8-16(13-22)10-17(9-15)14-22/h1-2,4-5,11,15-17H,3,6-10,12-14H2,(H,27,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	490	n/a	n/a	n/a	n/a
Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University , 3663 North Zhongshan Road, Shang Curated by ChEMBL					Assay Description Antagonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of CP55940-induced Ca2+ flux preincubated for 10 mins followe...				J Med Chem 60: 7067-7083 (2017) Article DOI: 10.1021/acs.jmedchem.7b00724 BindingDB Entry DOI: 10.7270/Q20K2C17
					More data for this Ligand-Target Pair