null

SMILES: Fc1ccc(cc1)C(=O)NCCN1CCC(CC1)n1c2ccc(Br)cc2[nH]c1=O

InChI Key: InChIKey=AVJLSXGOQNVYRT-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50258179   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phospholipase D2 (Homo sapiens (Human))	BDBM50258179 (CHEMBL521990 | N-(2-(4-(5-bromo-2-oxo-2,3-dihydro-...) Show SMILES Fc1ccc(cc1)C(=O)NCCN1CCC(CC1)n1c2ccc(Br)cc2[nH]c1=O Show InChI InChI=1S/C21H22BrFN4O2/c22-15-3-6-19-18(13-15)25-21(29)27(19)17-7-10-26(11-8-17)12-9-24-20(28)14-1-4-16(23)5-2-14/h1-6,13,17H,7-12H2,(H,24,28)(H,25,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt Specialized Chemistry Center Curated by PubChem BioAssay					Assay Description Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q21R6P4V
					More data for this Ligand-Target Pair
Phospholipase D1 (Homo sapiens (Human))	BDBM50258179 (CHEMBL521990 | N-(2-(4-(5-bromo-2-oxo-2,3-dihydro-...) Show SMILES Fc1ccc(cc1)C(=O)NCCN1CCC(CC1)n1c2ccc(Br)cc2[nH]c1=O Show InChI InChI=1S/C21H22BrFN4O2/c22-15-3-6-19-18(13-15)25-21(29)27(19)17-7-10-26(11-8-17)12-9-24-20(28)14-1-4-16(23)5-2-14/h1-6,13,17H,7-12H2,(H,24,28)(H,25,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of human PLD1 in Calu1 cells				Bioorg Med Chem Lett 19: 1916-20 (2009) Article DOI: 10.1016/j.bmcl.2009.02.057 BindingDB Entry DOI: 10.7270/Q2VM4C5W
					More data for this Ligand-Target Pair
Phospholipase D2 (Homo sapiens (Human))	BDBM50258179 (CHEMBL521990 | N-(2-(4-(5-bromo-2-oxo-2,3-dihydro-...) Show SMILES Fc1ccc(cc1)C(=O)NCCN1CCC(CC1)n1c2ccc(Br)cc2[nH]c1=O Show InChI InChI=1S/C21H22BrFN4O2/c22-15-3-6-19-18(13-15)25-21(29)27(19)17-7-10-26(11-8-17)12-9-24-20(28)14-1-4-16(23)5-2-14/h1-6,13,17H,7-12H2,(H,24,28)(H,25,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of GFP-labelled human PLD2 HEK293 cells				Bioorg Med Chem Lett 19: 1916-20 (2009) Article DOI: 10.1016/j.bmcl.2009.02.057 BindingDB Entry DOI: 10.7270/Q2VM4C5W
					More data for this Ligand-Target Pair
Phospholipase D1 (Homo sapiens (Human))	BDBM50258179 (CHEMBL521990 | N-(2-(4-(5-bromo-2-oxo-2,3-dihydro-...) Show SMILES Fc1ccc(cc1)C(=O)NCCN1CCC(CC1)n1c2ccc(Br)cc2[nH]c1=O Show InChI InChI=1S/C21H22BrFN4O2/c22-15-3-6-19-18(13-15)25-21(29)27(19)17-7-10-26(11-8-17)12-9-24-20(28)14-1-4-16(23)5-2-14/h1-6,13,17H,7-12H2,(H,24,28)(H,25,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt Specialized Chemistry Center Curated by PubChem BioAssay					Assay Description Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2NK3CNK
					More data for this Ligand-Target Pair