BDBM50258191 1-(Methylsulfonyl)-N-(6-phenylpyridin-3-yl)-1,2-dihydro-1'H-spiro[indole-3,4'-piperidine]-1'-carboxamide::1-(methylsulfonyl)-N-(6-phenylpyridin-3-yl)spiro[indoline-3,4'-piperidine]-1'-carboxamide::CHEMBL522540

SMILES: CS(=O)(=O)N1CC2(CCN(CC2)C(=O)Nc2ccc(nc2)-c2ccccc2)c2ccccc12

InChI Key: InChIKey=DWORNUFGAHPONA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50258191   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 5 ( NPY Y5) (Homo sapiens (Human))	BDBM50258191 (1-(Methylsulfonyl)-N-(6-phenylpyridin-3-yl)-1,2-di...) Show SMILES CS(=O)(=O)N1CC2(CCN(CC2)C(=O)Nc2ccc(nc2)-c2ccccc2)c2ccccc12 Show InChI InChI=1S/C25H26N4O3S/c1-33(31,32)29-18-25(21-9-5-6-10-23(21)29)13-15-28(16-14-25)24(30)27-20-11-12-22(26-17-20)19-7-3-2-4-8-19/h2-12,17H,13-16,18H2,1H3,(H,27,30)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.820	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Binding affinity to human neuropeptide Y5 receptor				Bioorg Med Chem 17: 5015-26 (2009) Article DOI: 10.1016/j.bmc.2009.05.064 BindingDB Entry DOI: 10.7270/Q2KK9BT2
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 ( NPY Y5) (Homo sapiens (Human))	BDBM50258191 (1-(Methylsulfonyl)-N-(6-phenylpyridin-3-yl)-1,2-di...) Show SMILES CS(=O)(=O)N1CC2(CCN(CC2)C(=O)Nc2ccc(nc2)-c2ccccc2)c2ccccc12 Show InChI InChI=1S/C25H26N4O3S/c1-33(31,32)29-18-25(21-9-5-6-10-23(21)29)13-15-28(16-14-25)24(30)27-20-11-12-22(26-17-20)19-7-3-2-4-8-19/h2-12,17H,13-16,18H2,1H3,(H,27,30)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.820	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human recombinant Y5 receptor expressed in mouse LMtk cells				Bioorg Med Chem Lett 19: 1564-8 (2009) Article DOI: 10.1016/j.bmcl.2009.02.035 BindingDB Entry DOI: 10.7270/Q2TQ61FT
					More data for this Ligand-Target Pair