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BDBM50258260 CHEMBL4079320

SMILES: COc1cccc(CNC(=O)c2cnn3cc(C)cnc23)c1

InChI Key: InChIKey=AKVFOYFUVUJANO-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50258260   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Homo sapiens phosphodiesterase 2A (PDE2A)


(Homo sapiens (Human))		BDBM50258260
PNG
(CHEMBL4079320)
Show SMILES COc1cccc(CNC(=O)c2cnn3cc(C)cnc23)c1
Show InChI InChI=1S/C16H16N4O2/c1-11-7-17-15-14(9-19-20(15)10-11)16(21)18-8-12-4-3-5-13(6-12)22-2/h3-7,9-10H,8H2,1-2H3,(H,18,21)
PDB

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PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited , 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.

Curated by ChEMBL


Assay Description
Inhibition of PDE2A (unknown origin)

J Med Chem 60: 7658-7676 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00709
BindingDB Entry DOI: 10.7270/Q2TT4TD5
More data for this
Ligand-Target Pair