BDBM50258294 2-[4-(7-Fluoropyrrolo[1,2-a]quinoxalin-4-yl)-piperazin-1-yl]acetamide::CHEMBL493183

SMILES: NC(=O)CN1CCN(CC1)c1nc2cc(F)ccc2n2cccc12

InChI Key: InChIKey=UXTATQQIFBDWOL-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50258294   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin (5-HT) receptor (RAT)	BDBM50258294 (2-[4-(7-Fluoropyrrolo[1,2-a]quinoxalin-4-yl)-piper...) Show SMILES NC(=O)CN1CCN(CC1)c1nc2cc(F)ccc2n2cccc12 Show InChI InChI=1S/C17H18FN5O/c18-12-3-4-14-13(10-12)20-17(15-2-1-5-23(14)15)22-8-6-21(7-9-22)11-16(19)24/h1-5,10H,6-9,11H2,(H2,19,24)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
European Research Centre for Drug Discovery and Development Curated by ChEMBL					Assay Description Displacement of [3H]LY278584 from 5HT3 receptor in rat cortical homogenate				J Med Chem 52: 3548-62 (2009) Article DOI: 10.1021/jm900018b BindingDB Entry DOI: 10.7270/Q2M908K7
					More data for this Ligand-Target Pair
HTR3A (GUINEA PIG)	BDBM50258294 (2-[4-(7-Fluoropyrrolo[1,2-a]quinoxalin-4-yl)-piper...) Show SMILES NC(=O)CN1CCN(CC1)c1nc2cc(F)ccc2n2cccc12 Show InChI InChI=1S/C17H18FN5O/c18-12-3-4-14-13(10-12)20-17(15-2-1-5-23(14)15)22-8-6-21(7-9-22)11-16(19)24/h1-5,10H,6-9,11H2,(H2,19,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.12E+4	n/a	n/a	n/a	n/a	n/a	n/a
European Research Centre for Drug Discovery and Development Curated by ChEMBL					Assay Description Antagonist activity at 5HT3 receptor in spontaneously beating guinea pig right atrium assessed as inhibition of serotonin-induced maximum response by...				J Med Chem 52: 3548-62 (2009) Article DOI: 10.1021/jm900018b BindingDB Entry DOI: 10.7270/Q2M908K7
					More data for this Ligand-Target Pair