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BDBM50258297 CHEMBL4076518

SMILES: CCC(NC(=O)c1cnn2cccnc12)c1ccc(OC)cc1

InChI Key: InChIKey=HLWUTURAWLKRHA-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50258297   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Homo sapiens phosphodiesterase 2A (PDE2A)


(Homo sapiens (Human))		BDBM50258297
PNG
(CHEMBL4076518)
Show SMILES CCC(NC(=O)c1cnn2cccnc12)c1ccc(OC)cc1
Show InChI InChI=1S/C17H18N4O2/c1-3-15(12-5-7-13(23-2)8-6-12)20-17(22)14-11-19-21-10-4-9-18-16(14)21/h4-11,15H,3H2,1-2H3,(H,20,22)
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.80E+3n/an/an/an/an/an/a



Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited , 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa 251-8555, Japan.

Curated by ChEMBL


Assay Description
Inhibition of PDE2A (unknown origin)

J Med Chem 60: 7658-7676 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00709
BindingDB Entry DOI: 10.7270/Q2TT4TD5
More data for this
Ligand-Target Pair