BDBM50258410 (R)-1-(3-chlorobenzyl)-N-((7R,8R)-8-(4-ethylphenylsulfonamido)-7-hydroxy-5,6,7,8-tetrahydronaphthalen-2-yl)pyrrolidine-2-carboxamide::CHEMBL524191

SMILES: CCc1ccc(cc1)S(=O)(=O)N[C@H]1[C@H](O)CCc2ccc(NC(=O)[C@H]3CCCN3Cc3cccc(Cl)c3)cc12

InChI Key: InChIKey=BFJDEOSAKWNDTO-MPFGFTFXSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50258410   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50258410 ((R)-1-(3-chlorobenzyl)-N-((7R,8R)-8-(4-ethylphenyl...) Show SMILES CCc1ccc(cc1)S(=O)(=O)N[C@H]1[C@H](O)CCc2ccc(NC(=O)[C@H]3CCCN3Cc3cccc(Cl)c3)cc12 |r| Show InChI InChI=1S/C30H34ClN3O4S/c1-2-20-8-13-25(14-9-20)39(37,38)33-29-26-18-24(12-10-22(26)11-15-28(29)35)32-30(36)27-7-4-16-34(27)19-21-5-3-6-23(31)17-21/h3,5-6,8-10,12-14,17-18,27-29,33,35H,2,4,7,11,15-16,19H2,1H3,(H,32,36)/t27-,28-,29-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Icagen Inc Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells by patch-clamp electrophysiology method				Bioorg Med Chem Lett 19: 3063-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.002 BindingDB Entry DOI: 10.7270/Q2ZS2WD4
					More data for this Ligand-Target Pair