BDBM50258503 CHEMBL466019::N-((7R,8R)-8-(4-tert-butylphenylsulfonamido)-7-hydroxy-5,6,7,8-tetrahydronaphthalen-2-yl)-3-methoxybenzamide

SMILES: COc1cccc(c1)C(=O)Nc1ccc2CC[C@@H](O)[C@H](NS(=O)(=O)c3ccc(cc3)C(C)(C)C)c2c1

InChI Key: InChIKey=DZLOLQBOFITCTA-CLJLJLNGSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50258503   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50258503 (CHEMBL466019 | N-((7R,8R)-8-(4-tert-butylphenylsul...) Show SMILES COc1cccc(c1)C(=O)Nc1ccc2CC[C@@H](O)[C@H](NS(=O)(=O)c3ccc(cc3)C(C)(C)C)c2c1 |r| Show InChI InChI=1S/C28H32N2O5S/c1-28(2,3)20-10-13-23(14-11-20)36(33,34)30-26-24-17-21(12-8-18(24)9-15-25(26)31)29-27(32)19-6-5-7-22(16-19)35-4/h5-8,10-14,16-17,25-26,30-31H,9,15H2,1-4H3,(H,29,32)/t25-,26-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Icagen Inc Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells by patch-clamp electrophysiology method				Bioorg Med Chem Lett 19: 3063-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.002 BindingDB Entry DOI: 10.7270/Q2ZS2WD4
					More data for this Ligand-Target Pair