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BDBM50258571 CHEMBL466429::N-(4-Fluorophenylethyl)-1-benzyl-1,8-naphthyridin-2(1H)-on-3-carboxamide

SMILES: Fc1ccc(CCNC(=O)c2cc3cccnc3n(Cc3ccccc3)c2=O)cc1

InChI Key: InChIKey=SHVOOPWAUHCAOR-UHFFFAOYSA-N

Data: 2 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50258571   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50258571
PNG
(CHEMBL466429 | N-(4-Fluorophenylethyl)-1-benzyl-1,...)
Show SMILES Fc1ccc(CCNC(=O)c2cc3cccnc3n(Cc3ccccc3)c2=O)cc1
Show InChI InChI=1S/C24H20FN3O2/c25-20-10-8-17(9-11-20)12-14-27-23(29)21-15-19-7-4-13-26-22(19)28(24(21)30)16-18-5-2-1-3-6-18/h1-11,13,15H,12,14,16H2,(H,27,29)
PDB

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PC cid
PC sid
UniChem

Similars

Article
PubMed
69.8n/an/an/an/an/an/an/an/a



Universita di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells


J Med Chem 52: 3644-51 (2009)


Article DOI: 10.1021/jm801563d
BindingDB Entry DOI: 10.7270/Q2X0680K
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50258571
PNG
(CHEMBL466429 | N-(4-Fluorophenylethyl)-1-benzyl-1,...)
Show SMILES Fc1ccc(CCNC(=O)c2cc3cccnc3n(Cc3ccccc3)c2=O)cc1
Show InChI InChI=1S/C24H20FN3O2/c25-20-10-8-17(9-11-20)12-14-27-23(29)21-15-19-7-4-13-26-22(19)28(24(21)30)16-18-5-2-1-3-6-18/h1-11,13,15H,12,14,16H2,(H,27,29)
PDB

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KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
6.95E+3n/an/an/an/an/an/an/an/a



Universita di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in HEK293 cells


J Med Chem 52: 3644-51 (2009)


Article DOI: 10.1021/jm801563d
BindingDB Entry DOI: 10.7270/Q2X0680K
More data for this
Ligand-Target Pair