BDBM50258758 CHEMBL466646::benzyl (7R,8R)-8-(4-ethylphenylsulfonamido)-7-hydroxy-5,6,7,8-tetrahydronaphthalen-2-ylcarbamate

SMILES: CCc1ccc(cc1)S(=O)(=O)N[C@H]1[C@H](O)CCc2ccc(NC(=O)OCc3ccccc3)cc12

InChI Key: InChIKey=NCYOTRLUVVIBFO-JWQCQUIFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50258758   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50258758 (CHEMBL466646 | benzyl (7R,8R)-8-(4-ethylphenylsulf...) Show SMILES CCc1ccc(cc1)S(=O)(=O)N[C@H]1[C@H](O)CCc2ccc(NC(=O)OCc3ccccc3)cc12 |r| Show InChI InChI=1S/C26H28N2O5S/c1-2-18-8-13-22(14-9-18)34(31,32)28-25-23-16-21(12-10-20(23)11-15-24(25)29)27-26(30)33-17-19-6-4-3-5-7-19/h3-10,12-14,16,24-25,28-29H,2,11,15,17H2,1H3,(H,27,30)/t24-,25-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Icagen Inc Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in mouse L929 cells by patch-clamp electrophysiology method				Bioorg Med Chem Lett 19: 3063-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.002 BindingDB Entry DOI: 10.7270/Q2ZS2WD4
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