BDBM50258807 CHEMBL4085745

SMILES: Oc1cccc(c1)-c1cccc(NC(=O)Nc2ccc(Cl)cc2)c1

InChI Key: InChIKey=REYVCEPLQOPGTM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50258807   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50258807 (CHEMBL4085745) Show SMILES Oc1cccc(c1)-c1cccc(NC(=O)Nc2ccc(Cl)cc2)c1 Show InChI InChI=1S/C19H15ClN2O2/c20-15-7-9-16(10-8-15)21-19(24)22-17-5-1-3-13(11-17)14-4-2-6-18(23)12-14/h1-12,23H,(H2,21,22,24)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	840	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute , Research Triangle Park, North Carolina 27709, United States. Curated by ChEMBL					Assay Description Allosteric modulation of human CB1 receptor expressed in CHO cells co-expressing Galpha16 assessed as inhibition of CP55,940-induced calcium mobiliza...				J Med Chem 60: 7410-7424 (2017) Article DOI: 10.1021/acs.jmedchem.7b00707 BindingDB Entry DOI: 10.7270/Q2XK8J0H
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