BDBM50258816 (S)-2-amino-N-(3-(1-methyl-4-(5-phenyl-1,3,4-oxadiazol-2-yl)-1H-pyrazol-5-yl)benzyl)propanamide::CHEMBL466637

SMILES: C[C@H](N)C(=O)NCc1cccc(c1)-c1c(cnn1C)-c1nnc(o1)-c1ccccc1

InChI Key: InChIKey=VBCSZLNSQITIIS-AWEZNQCLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50258816   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone-arginine methyltransferase CARM1 (Homo sapiens (Human))	BDBM50258816 ((S)-2-amino-N-(3-(1-methyl-4-(5-phenyl-1,3,4-oxadi...) Show SMILES C[C@H](N)C(=O)NCc1cccc(c1)-c1c(cnn1C)-c1nnc(o1)-c1ccccc1 |r| Show InChI InChI=1S/C22H22N6O2/c1-14(23)20(29)24-12-15-7-6-10-17(11-15)19-18(13-25-28(19)2)22-27-26-21(30-22)16-8-4-3-5-9-16/h3-11,13-14H,12,23H2,1-2H3,(H,24,29)/t14-/m0/s1	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of CARM1 assessed as blockade of histone H3 methylation				Bioorg Med Chem Lett 19: 2924-7 (2009) Article DOI: 10.1016/j.bmcl.2009.04.075 BindingDB Entry DOI: 10.7270/Q24B3170
					More data for this Ligand-Target Pair